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Article

MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands.

Molecular microbiology - 1 Dec 2006

Xiao Gaoping, Déziel Eric, He Jianxin, Lépine François, Lesic Biliana, Castonguay Marie-Hélène, Milot Sylvain, Tampakaki Anastasia P, Stachel Scott E, Rahme Laurence G

Abstract excerpt

MvfR (PqsR), a Pseudomonas aeruginosa LysR-type transcriptional regulator, plays a critical role in the virulence of this pathogen. MvfR modulates the expression of multiple quorum sensing (QS)-regulated virulence factors; and the expression of the phnAB and pqsA-E genes that encode functions mediating 4-hydroxy-2-alkylquinolines (HAQs) signalling compounds biosynthesis, including 3,4-dihydroxy-2heptylquinoline...

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PMID: 17083468
DOI: 10.1111/j.1365-2958.2006.05462.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands.PMID 17083468Read ↗

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A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism.Semantic proximity Read ↗

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