Article
The peptide chain release factor methyltransferase PrmC is essential for pathogenicity and environmental adaptation of Pseudomonas aeruginosa PA14.
Environmental microbiology - 1 Feb 2013
Pustelny Christian, Brouwer Stephan, Müsken Mathias, Bielecka Agata, Dötsch Andreas, Nimtz Manfred, Häussler Susanne
Abstract excerpt
Pseudomonas aeruginosa pathogenicity and its capability to adapt to multiple environments are dependent on the production of diverse virulence factors, controlled by the sophisticated quorum sensing (QS) network of P. aeruginosa. To better understand the molecular mechanisms that underlie this adaptation we searched for novel key regulators of virulence factor production by screening a PA14 transposon mutant...
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