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Article

Alternative splicing of DSP1 enhances snRNA accumulation by promoting transcription termination and recycle of the processing complex.

Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 2020

Wang Weili, Pu Xuepiao, Yang Siyu, Feng Yujie, Lin Chan, Li Mu, Li Xi, Li Huali, Meng Chunmei, Xie Qingjun, Yu Bin, Liu Yunfeng

Abstract excerpt

Small nuclear RNAs (snRNAs) are the basal components of the spliceosome and play crucial roles in splicing. Their biogenesis is spatiotemporally regulated. However, related mechanisms are still poorly understood. Defective in snRNA processing (DSP1) is an essential component of the DSP1 complex that catalyzes plant snRNA 3'-end maturation by cotranscriptional endonucleolytic cleavage of the primary snRNA...

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Identifiers

PMID: 32747542
DOI: 10.1073/pnas.2002115117
PMCID: PMC7443885

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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