The STA1-DOT2 interaction promotes nuclear speckle formation and splicing robustness in growth and heat stress responses.

Abstract excerpt

Pre-mRNA splicing is carried out by the spliceosome, a large and dynamic ribonucleoprotein complex. The spliceosome is known to be stored in nuclear speckles (NS), which are recognized as active subnuclear organelles for splicing. However, it remains poorly understood how spliceosomal protein-protein interactions are functionally coupled to NS organization to maintain splicing robustness in plants. Here, we...

Topics

Join the communities discussing this publication.

• Arabidopsis
• Arabidopsis Proteins
• Gene Expression Regulation, Plant
• Heat-Shock Response
• Mutation