Article
Many loci make light work: High individual diversity despite low population diversity and random mating at class I MHC in a Critically Endangered island songbird.
Molecular ecology - 1 Oct 2020
MacDougall-Shackleton Elizabeth A
Abstract excerpt
Multi-cellular organisms are under constant attack from parasites, making immune defence a critical aspect of fitness. In vertebrate animals, genes of the major histocompatibility complex (MHC) determine the breadth of pathogens to which individuals can respond. Having many MHC alleles can confer better protection against infectious disease, and balancing selection at MHC is widespread. Indeed, MHC loci are...
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