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Article

High MHC diversity confers no advantage for phenotypic quality and reproductive performance in a wild bird.

The Journal of animal ecology - 1 Aug 2022

Pikus Ewa, Dunn Peter O, Minias Piotr

Abstract excerpt

Genes of the major histocompatibility complex (MHC) encode antigen-binding molecules and are an integral part of the acquired immune response of vertebrates. In general, high individual MHC diversity is expected to increase fitness by broadening the spectrum of pathogens recognized by the immune system, in accordance with the heterozygote advantage mechanism. On the other hand, the optimality hypothesis assumes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35521665
DOI: 10.1111/1365-2656.13737
PMCID: PMC9542035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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