Article
Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy.
Bioscience reports - 28 Aug 2020
Liu Yu-Huei, Shen Chiou-Yuan, Tsai Fuu-Jen
Abstract excerpt
The macrophage migration inhibitory factor (MIF)/cluster of differentiation 74 (CD74) plays a role in immunological functions. The present study aims to investigate whether single-nucleotide polymorphisms (SNPs) in the MIF and CD74 are risk factors for developing Graves ophthalmopathy (GO) in patients with Graves disease (GD). A case-control study enrolled 484 patients with GD (203 with and 281 without GO) and...
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