Article
Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span.
Cold Spring Harbor perspectives in medicine - 4 Dec 2015
Milman Sofiya, Barzilai Nir
Abstract excerpt
Humans age at different rates and families with exceptional survival provide the opportunity to understand why some people age slower than others. Unique features exhibited by centenarians include a family history of longevity, compression of morbidity with resultant extension of health span, and biomarkers such as low-circulating insulin-like growth factor 1 (IGF-1) and elevated high-density lipoprotein (HDL)...
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