Article
Genetics of exceptional longevity.
Experimental gerontology - 1 Jul 2003
Perls Thomas, Terry Dellara
Abstract excerpt
Centenarians exist at the extreme of life expectancy and are rare. A number of pedigree and molecular genetic studies indicate that a significant component of exceptional longevity is genetically influenced. Furthermore, the recent discovery of a genetic locus on chromosome 4 indicates the powerful potential of studying centenarians for genetic factors that significantly modulate aging and susceptibility to...
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