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Article

The Role of Noncoding Variants in Heritable Disease.

Trends in genetics : TIG - 1 Nov 2020

French J D, Edwards S L

Abstract excerpt

The genetic basis of disease has largely focused on coding regions. However, it has become clear that a large proportion of the noncoding genome is functional and harbors genetic variants that contribute to disease etiology. Here, we review recent examples of inherited noncoding alterations that are responsible for Mendelian disorders or act to influence complex traits. We explore both rare and common genetic...

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Identifiers

PMID: 32741549
DOI: 10.1016/j.tig.2020.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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