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Article

Searching for functional genetic variants in non-coding DNA.

Clinical and experimental pharmacology & physiology - 1 Apr 2008

Cobb Joanna, Büsst Cara, Petrou Steven, Harrap Stephen, Ellis Justine

Abstract excerpt

1. The search for DNA sequence variants for complex human polygenic conditions has been a strong focus of recent genetic research. While gene loci have been identified, few variants in the coding sequences of these genes have been found, suggesting that non-coding sequence variation may underlie many complex conditions. 2. Non-coding DNA harbours regulatory elements capable of making changes to gene expression....

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PMID: 18307723
DOI: 10.1111/j.1440-1681.2008.04880.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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