Article
Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.
Journal of translational medicine - 1 Aug 2020
Li Jiaping, Jiang Wei, Wei Jinwang, Zhang Jianwei, Cai Linbo, Luo Minjie, Wang Zhan, Sun Wending, Wang Shengzhou, Wang Chen, Dai Chun, Liu Jun, Wang Guan, Wang Jiping, Xu Qiang, Deng Yanhong
Abstract excerpt
BACKGROUND: Circulating tumor DNA (ctDNA) offers a convenient way to monitor tumor progression and treatment response. Because tumor mutational profiles are highly variable from person to person, a fixed content panel may be insufficient to track treatment response in all patients. METHODS: We design ctDNA fingerprint panels specific to individual patients which are based on whole exome sequencing and target to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
