A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition.

doi:10.1016/j.chom.2020.06.020

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A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition.

Cell host & microbe - 9 Sept 2020

Dieterle M Eugenia, Haslwanter Denise, Bortz Robert H, Wirchnianski Ariel S, Lasso Gorka, Vergnolle Olivia, Abbasi Shawn A, Fels J Maximilian, Laudermilch Ethan, Florez Catalina, Mengotto Amanda, Kimmel Duncan, Malonis Ryan J, Georgiev George, Quiroz Jose, Barnhill Jason, Pirofski Liise-Anne, Daily Johanna P, Dye John M, Lai Jonathan R, Herbert Andrew S, Chandran Kartik, Jangra Rohit K

Abstract excerpt

There is an urgent need for vaccines and therapeutics to prevent and treat COVID-19. Rapid SARS-CoV-2 countermeasure development is contingent on the availability of robust, scalable, and readily deployable surrogate viral assays to screen antiviral humoral responses, define correlates of immune protection, and down-select candidate antivirals. Here, we generate a highly infectious recombinant vesicular...

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Identifiers

PMID: 32738193
DOI: 10.1016/j.chom.2020.06.020
PMCID: PMC7332447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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