How to make a functional β-cell

Abstract excerpt

Insulin-secreting pancreatic β-cells are essential regulators of mammalian metabolism. The absence of functional β-cells leads to hyperglycemia and diabetes, making patients dependent on exogenously supplied insulin. Recent insights into β-cell development, combined with the discovery of pluripotent stem cells, have led to an unprecedented opportunity to generate new β-cells for transplantation therapy and drug...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Diabetes Management and Research
• Share to Pancreatic function and diabetes
• Share to Pluripotent Stem Cells Research