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Article

Nrf2 mediates redox adaptations to exercise

17 Oct 2016

Abstract excerpt

The primary aim of this review is to summarize the current literature on the effects of acute exercise and regular exercise on nuclear factor erythroid 2-related factor 2 (Nrf2) activity and downstream targets of Nrf2 signaling. Nrf2 (encoded in humans by the NFE2L2 gene) is the master regulator of antioxidant defenses, a transcription factor that regulates expression of more than 200 cytoprotective genes....

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PMID: 27770706
DOI: 10.1016/j.redox.2016.10.003

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