Article
The importance of IDH1, ATRX and WT-1 mutations in glioblastoma.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jan 2020
Gülten Gülsün, Yalçın Nagİhan, Baltalarlı Bahar, Doğu Gamze, Acar Ferİdun, Doğruel Yücel
Abstract excerpt
Numerous genetic pathways associated with glioblastoma development have been identified. In this study, we investigated the prognostic significance of IDH1 and ATRX mutations and WT-1 and p53 expression in glioblastomas and that of surgical methods, radiotherapy and chemotherapy. 83 patients with glioblastomas were retrospectively evaluated. Immunohistochemical analysis was performed for IDH1, ATRX and WT-1...
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