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Article

Variants of SLC22A16 Predict the Efficacy of Platinum Combination Chemotherapy in Advanced Non-small-cell Lung Cancer.

Anticancer research - 1 Aug 2020

Takeuchi Akira, Oguri Tetsuya, Fukuda Satoshi, Sone Kazuki, Kagawa Yusuke, Uemura Takehiro, Takakuwa Osamu, Maeno Ken, Fukumitsu Kensuke, Kanemitsu Yoshihiro, Tajiri Tomoko, Ohkubo Hirotsugu, Takemura Masaya, Ito Yutaka, Niimi Akio

Abstract excerpt

BACKGROUND: Organic cation transporter 6 (OCT6) encoded by solute carrier family 22 member 16 (SLC22A16) is involved in regulating cellular sensitivity and resistance to platinum derivatives. SLC22A16 has functional genetic variants but the association between these variants and the effectiveness of antitumor drugs remains unexplored. PATIENTS AND METHODS: This study retrospectively analyzed data from 160...

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Identifiers

PMID: 32727751
DOI: 10.21873/anticanres.14426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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