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Article

Effect of transporter and DNA repair gene polymorphisms to lung cancer chemotherapy toxicity.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2016

Chen Juan, Wu Lin, Wang Ying, Yin Jiye, Li Xiangping, Wang Zhan, Li Huihua, Zou Ting, Qian Chenyue, Li Chuntian, Zhang Wei, Zhou Honghao, Liu Zhaoqian

Abstract excerpt

Lung cancer is the first leading cause of cancer deaths. Chemotherapy toxicity is one of factors that limited the efficacy of platinum-based chemotherapy in lung cancer patients. Transporters and DNA repair genes play critical roles in occurrence of platinum-based chemotherapy toxicity. To investigate the relationships between transporter and DNA repair gene polymorphisms and platinum-based chemotherapy toxicity...

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Source

Identifiers

PMID: 26358256
DOI: 10.1007/s13277-015-4048-0

Genes

AQP2
XRCC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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