Article
TP53 codon 72 polymorphism and P53 protein expression in colorectal cancer specimens in Isfahan.
Acta medica Iranica - 1 Jan 2011
Dastjerdi Mehdi Nikbahkt
Abstract excerpt
UNLABELLED: The TP53 tumor suppressor gene plays important roles in genomic stability. A common polymorphism at codon 72 of TP53 gene has been associated with increased risk for many human cancers. The p53 protein is expressed in colorectal cancer, but the reported prevalence of its expression varies widely. In the present study, the p53 protein expression in different genotypes of its codon 72 , was...
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