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Multiple formin proteins participate in glioblastoma migration

29 Jul 2020

Abstract excerpt

BACKGROUND: The prognosis of glioblastoma remains poor, related to its diffuse spread within the brain. There is an ongoing search for molecular regulators of this particularly invasive behavior. One approach is to look for actin regulating proteins that might be targeted by future anti-cancer therapy. The formin family of proteins orchestrates rearrangement of the actin cytoskeleton in multiple cellular...

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PMID: 32727404
DOI: 10.1186/s12885-020-07211-7

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