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Article

Sex chromosome complement influences vulnerability to cocaine in mice.

Hormones and behavior - 1 Sept 2020

Martini Mariangela, Irvin Joshua W, Lee Christina G, Lynch Wendy J, Rissman Emilie F

Abstract excerpt

Women acquire cocaine habits faster and are more motivated to obtain drug than men. In general, female rodents acquire intravenous cocaine self-administration (SA) faster and show greater locomotor responses to cocaine than males. Sex differences are attributed to differences in circulating estradiol. We used the four core genotype (FCG) mouse to ask whether sex chromosome complement influences vulnerability to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32721403
DOI: 10.1016/j.yhbeh.2020.104821
PMCID: PMC7541729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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