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Novel insights on targeting ferroptosis in cancer therapy

2 Oct 2020

Abstract excerpt

Ferroptosis belongs to a novel form of regulated cell death. It is characterized by iron dependence, destruction of intracellular redox balance and non-apoptosis. And cellular structure and molecules level changes also occur abnormally during ferroptosis. It has been proved that ferroptosis exist widespreadly in many diseases, such as heart disease, brain damage or alzheimer disease. At the same time, the role of...

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PMID: 33024562
DOI: 10.1186/s40364-020-00229-w

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