Article
Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole.
BMC pharmacology & toxicology - 25 Jul 2020
Ochoa Dolores, Román Manuel, Cabaleiro Teresa, Saiz-Rodríguez Miriam, Mejía Gina, Abad-Santos Francisco
Abstract excerpt
BACKGROUND: The pharmacokinetics of proton pump inhibitors (PPIs) may be affected by food intake. We aimed to evaluate the effect of food on the pharmacokinetics of omeprazole, rabeprazole, and pantoprazole. SETTING: The study population comprised 186 healthy volunteers participating in 6 bioequivalence clinical trials. METHOD: Subjects were evaluated to determine the effect of a high-fat breakfast on the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
