Article
Effect of water intake on pharmacokinetics of lansoprazole from fast disintegrating tablet in human subjects.
Drug metabolism and pharmacokinetics - 1 Oct 2004
Iwasaki Koji, Ito Yukako, Shibata Nobuhito, Takada Kanji, Sakurai Yuichi, Takagi Naoshi, Irie Shin, Nakamura Koichi
Abstract excerpt
Lansoprazole fast disintegrating tablet (LFDT) has been developed as a multiple unit formulation to increase the QOL of patients, i.e., easy intake without water. However, there is a possibility that patients intake LFDT in accordance with clarithromycin and amoxicillin with water. To study the effect of water on the absorption of lansoprazole (LPZ), the study was carried out using human volunteers. After...
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