Article
Pharmacokinetic Profiles of Lansoprazole in Patients With Morbid Obesity Post-Roux-en-Y Gastric Bypass Surgery.
Clinical and translational science - 1 Mar 2025
Udomsawaengsup Suthep, Chantawibul Sathienrapong, Boonyuen Naranon, Panyavorakhunchai Sarunnuch, Kachornvitaya Pattharasai, Wisanuyothin Wasu, Somvanapanich Pittawat, Lertwatthiphong Warittha, Tanathitiphuwarat Napatsanan, Chariyavilaskul Pajaree
Abstract excerpt
Data on the effects of Roux-en-Y gastric bypass (RYGB) surgery on lansoprazole pharmacokinetics in morbidly obese patients are limited. This study aimed to evaluate the impact of RYGB surgery on the pharmacokinetic profile of lansoprazole in Thai morbidly obese patients. Participants received 30 mg of lansoprazole twice daily for 7 days before surgery and continued the regimen for 6 weeks post-surgery. Plasma...
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