Article
Approaches for the identification of driver mutations in cancer: A tutorial from a computational perspective.
Journal of bioinformatics and computational biology - 1 Jun 2020
Cutigi Jorge Francisco, Evangelista Adriane Feijo, Simao Adenilso
Abstract excerpt
Cancer is a complex disease caused by the accumulation of genetic alterations during the individual's life. Such alterations are called genetic mutations and can be divided into two groups: (1) Passenger mutations, which are not responsible for cancer and (2) Driver mutations, which are significant for cancer and responsible for its initiation and progression. Cancer cells undergo a large number of mutations, of...
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