Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.

Genes - 20 Jul 2020

Vesa Stefan Cristian, Vlaicu Sonia Irina, Vacaras Vitalie, Crisan Sorin, Sabin Octavia, Pasca Sergiu, Trifa Adrian Pavel, Rusz-Fogarasi Tamas, Sava Madalina, Buzoianu Anca Dana

Abstract excerpt

INTRODUCTION: Atherosclerosis represents the process by which fibrous plaques are formed in the arterial wall, increasing its rigidity with a subsequent decrease in blood flow which can lead to several cardiovascular events. Seeing as vitamin K antagonists are involved in the pathogenesis of atherosclerosis, we decided to investigate whether polymorphisms in genes that influence vitamin K metabolism might have an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carotid Artery Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P450 Family 4

Share to Plaque, Atherosclerotic

Share to Polymorphism, Single Nucleotide

Share to Vitamin K Epoxide Reductases

Source

Open in PubMed Open full text

Identifiers

PMID: 32698322
DOI: 10.3390/genes11070822
PMCID: PMC7396977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.PMID 32698322Read ↗

Association among VKORC1 rs9923231, CYP4F2 rs2108622, GGCX rs11676382 polymorphisms and acute ischemic stroke.Semantic proximity Read ↗

PCSK9 Protein and rs562556 Polymorphism Are Associated With Arterial Plaques in Healthy Middle-Aged Population: The STANISLAS Cohort.Semantic proximity Read ↗

VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification.Semantic proximity Read ↗

VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).Semantic proximity Read ↗

Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype.Semantic proximity Read ↗

VKORC1 rs2359612 and rs9923231 polymorphisms correlate with high risks of cardiovascular and cerebrovascular diseases.Semantic proximity Read ↗

Matrix metalloproteinase-1 promoter genotypes and haplotypes are associated with carotid plaque presence.Semantic proximity Read ↗

Carotid plaque and candidate genes related to inflammation and endothelial function in Hispanics from northern Manhattan.Semantic proximity Read ↗

Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans.Semantic proximity Read ↗

Human carotid plaque phosphatidylcholine specifically interacts with paraoxonase 1, increases its activity, and enhances its uptake by macrophage at the expense of its binding to HDL.Semantic proximity Read ↗

Internal carotid artery occlusive disease and polymorphisms of fractalkine receptor CX3CR1: a genetic risk factor.Semantic proximity Read ↗

Association between variations in coagulation system genes and carotid plaque.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.