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Article

Association among VKORC1 rs9923231, CYP4F2 rs2108622, GGCX rs11676382 polymorphisms and acute ischemic stroke.

Medicine - 25 Aug 2023

Iluţ Silvina, Vesa Ştefan Cristian, Văcăraş Vitalie, Şipoş-Lascu Diana, Bârsan Cristina, Pop Raluca Maria, Crişan Sorin, Macarie Antonia Eugenia, Coadă Camelia Alexandra, Perju-Dumbravă Lăcrămioara, Muresanu Dafin Fior, Buzoianu Anca Dana

Abstract excerpt

Acute ischemic stroke is a major cause of morbidity and mortality worldwide, and genetic factors play a role in the risk of stroke. Single nucleotide polymorphisms (SNPs) in the VKORC1, CYP4F2, and GGCX genes have been linked to clinical outcomes, such as bleeding and cardiovascular diseases. This study aimed to investigate the association between specific polymorphisms in these genes and the risk of developing...

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PMID: 37653796
DOI: 10.1097/MD.0000000000034836
PMCID: PMC10470791

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