Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification.

Human genetics - 1 Jan 2013

Wang Yibo, Chen Jinxing, Zhang Yu, Bin Lv, Sun Kai, Yu Weifeng, Liu Jibin, Zhang Channa, Shen Haiqing, Hou Zhihui, Yu Fangfang, Hui Rutai

Abstract excerpt

VKORC1 genetic polymorphisms affect warfarin dose response, aortic calcification, and the susceptibility of coronary artery disease as shown in our previous study. Little is known regarding the association of VKORC1 polymorphisms with coronary artery calcification (CAC) and the role of CAC in the association with coronary artery disease (CAD). Due to a natural haplotype block in the VKORC1 gene in Chinese,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Calcinosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Coronary Artery Disease

Share to Genetic Association Studies

Share to Mixed Function Oxygenases

Share to Vitamin K Epoxide Reductases

Source

Identifiers

PMID: 22915323
DOI: 10.1007/s00439-012-1222-y

Genes

CAD
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VKORC1 rs2359612C allele is associated with increased risk of coronary artery disease in the presence of coronary calcification.PMID 22915323Read ↗

Vitamin K epoxide reductase complex subunit 1 (VKORC1) polymorphism and aortic calcification: the Rotterdam Study.Semantic proximity Read ↗

Association of NPC1L1 and HMGCR gene polymorphisms with coronary artery calcification in patients with premature triple-vessel coronary disease.Semantic proximity Read ↗

Sequence variation in vitamin K epoxide reductase gene is associated with survival and progressive coronary calcification in chronic kidney disease.Semantic proximity Read ↗

VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection).Semantic proximity Read ↗

VKORC1 gene (vitamin K epoxide reductase) polymorphisms are associated with cardiovascular disease in chronic kidney disease patients on hemodialysis.Semantic proximity Read ↗

Missense mutation of VKORC1 leads to medial arterial calcification in rats.Semantic proximity Read ↗

CYP4F2 and VKORC1 Polymorphisms Amplify the Risk of Carotid Plaque Formation.Semantic proximity Read ↗

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.Semantic proximity Read ↗

VKORC1 rs2359612 and rs9923231 polymorphisms correlate with high risks of cardiovascular and cerebrovascular diseases.Semantic proximity Read ↗

Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype.Semantic proximity Read ↗

Shared and discrepant susceptibility for carotid artery and aortic arch calcification: A genetic association study.Semantic proximity Read ↗

Susceptiveness of Vitamin K epOxide Reductase Complex Subunit 1 Gene Polymorphism in Essential Hypertension.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.