Article
[Evaluating the causal relationship between hip circumference and coronary heart disease: a Mendelian randomization study].
Wei sheng yan jiu = Journal of hygiene research - 1 May 2020
Yuan Tonghui, Li Hongkai, Ma Yuntao, Si Shucheng, Liu Xinhui, Yu Yuanyuan, Li Yunxia, Li Wenchao, Hou Lei, Liu Lu, Zhou Yuchang, Xue Fuzhong, Wang Ping, Liu Yanxun
Abstract excerpt
OBJECTIVE: To test the causal effect of hip circumference adjusted for body mass index(HCadjBMI) and coronary heart disease(CHD) using a Mendelian randomization analysis. METHODS: Based on genome-wide association study, the associations between the genetic instruments(IVs) and HCadjBMI were obtained from the GIANT consortium(n=211 114, European), the associations between IVs and CHD were derided from CARDIoGRAM...
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