Article
Waist circumference increases risk of coronary heart disease: Evidence from a Mendelian randomization study.
Molecular genetics & genomic medicine - 1 Apr 2020
Chen Qinchang, Li Lingling, Yi Junzhe, Huang Kai, Shen Runnan, Wu Ridong, Yao Chen
Abstract excerpt
BACKGROUND: This study investigated whether expanding waist circumference (WC) is causally associated with an elevated risk of coronary heart disease (CHD), using a two-sample Mendelian randomization (MR) study through integrating summarized data from genome-wide association study. METHODS: The data included in this analysis were mainly from the Genetic Investigation of ANthropometric Traits (GIANT), Consortium...
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