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Article

Cardiovascular health, genetic risk, and risk of dementia in the Framingham Heart Study.

Neurology - 8 Sept 2020

Peloso Gina M, Beiser Alexa S, Satizabal Claudia L, Xanthakis Vanessa, Vasan Ramachandran S, Pase Matthew P, Destefano Anita L, Seshadri Sudha

Abstract excerpt

OBJECTIVE: To determine the joint role of ideal cardiovascular health (CVH) and genetic risk on risk of dementia. METHODS: We categorized CVH on the basis of the American Heart Association Ideal CVH Index and genetic risk through a genetic risk score (GRS) of common genetic variants and the APOE ε4 genotype in 1,211 Framingham Heart Study (FHS) offspring cohort participants. We used multivariable Cox proportional...

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Identifiers

PMID: 32690788
DOI: 10.1212/WNL.0000000000010306
PMCID: PMC7538213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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