Article
Androgenetic Complete Hydatidiform Moles With p57KIP2-Positive Immunostaining.
American journal of clinical pathology - 4 Nov 2020
Usui Hirokazu, Sato Asuka, Ota Masayuki, Ikeda Jun-Ichiro, Shozu Makio
Abstract excerpt
OBJECTIVES: Complete hydatidiform moles (CHMs) are androgenetic and have a high rate of progression to gestational trophoblastic neoplasia (GTN). CHMs are negative when immunostained for p57KIP2 protein, the product of the maternally expressed gene on chromosome 11p15.5, whereas biparental partial hydatidiform moles and hydropic abortion are positive for p57KIP2. This study presents two cases of p57KIP2-positive...
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