Article
Characterization of androgenetic/biparental mosaic/chimeric conceptions, including those with a molar component: morphology, p57 immnohistochemistry, molecular genotyping, and risk of persistent gestational trophoblastic disease.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Mar 2013
Lewis Gloria H, DeScipio Cheryl, Murphy Kathleen M, Haley Lisa, Beierl Katie, Mosier Stacy, Tandy Sharon, Cohen Debra S, Lytwyn Alice, Elit Laurie, Vang Russell, Ronnett Brigitte M
Abstract excerpt
Recent studies have demonstrated the value of ancillary techniques, including p57 immunohistochemistry and short tandem repeat genotyping, for distinguishing hydatidiform moles (HM) from nonmolar specimens and for subtyping HMs as complete hydatidiform moles (CHM) and partial hydatidiform moles (PHM). With rare exceptions, CHMs are p57-negative and androgenetic diploid; partial hydatidiform moles are p57-positive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
