Article
Multiplex short tandem repeat DNA analysis confirms the accuracy of p57(KIP2) immunostaining in the diagnosis of complete hydatidiform mole.
Human pathology - 1 Nov 2006
Popiolek Dorota A, Yee Herman, Mittal Khush, Chiriboga Luis, Prinz Mechthild K, Caragine Theresa A, Budimlija Zoran M
Abstract excerpt
Detailed histopathologic examination remains to be the basis for the diagnosis of hydatidiform mole (HM). However, poor sampling, necrosis, and earlier uterine evacuation can lead to uncertainty in the diagnosis. Also, the criteria are subjective, resulting in considerable interobserver variability. The p57(KIP2) gene is paternally imprinted and maternally expressed, and the presence of its protein product serves...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
