Comprehensive analysis of 204 sporadic hydatidiform moles: revisiting risk factors and their correlations with the molar genotypes.

doi:10.1038/s41379-019-0432-4

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Article

Comprehensive analysis of 204 sporadic hydatidiform moles: revisiting risk factors and their correlations with the molar genotypes.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2020

Khawajkie Yassemine, Mechtouf Nawel, Nguyen Ngoc Minh Phuong, Rahimi Kurosh, Breguet Magali, Arseneau Jocelyne, Ronnett Brigitte M, Hoffner Lori, Lazure Felicia, Arnaud Marjolaine, Peers Fabrice, Tan Liane, Rafea Basam Abu, Aguinaga Monica, Horowitz Neil S, Ao Asangla, Tan Seang Lin, Brown Richard, Buckett William, Surti Urvashi, Hovanes Karine, Sahoo Trilochan, Sauthier Philippe, Slim Rima

Abstract excerpt

Hydatidiform mole (HM) is an aberrant human pregnancy characterized by excessive trophoblastic proliferation and abnormal embryonic development. HM has two morphological types, complete (CHM) and partial (PHM), and non-recurrent ones have three genotypic types, androgenetic monospermic, androgenetic dispermic, and triploid dispermic. Most available studies on risk factors predisposing to different types of HM and...

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PMID: 31857680
DOI: 10.1038/s41379-019-0432-4

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