Article
Invasive Complete Hydatidiform Moles: Analysis of a Case Series With Genotyping.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Mar 2016
Bynum Jennifer, Murphy Kathleen M, DeScipio Cheryl, Beierl Katie, Adams Emily, Anderson Derek, Vang Russell, Ronnett Brigitte M
Abstract excerpt
Complete hydatidiform moles (CHM) are purely androgenetic conceptions, with most (∼85%) arising from fertilization of an egg lacking maternal DNA by a single sperm that duplicates (homozygous/monospermic 46,XX) and a small subset arising via fertilization by 2 sperms (heterozygous/dispermic 46,XY or 46,XX). It remains controversial if heterozygous/dispermic CHMs have a significantly greater risk of persistent...
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