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Article

ABCB1, ABCG2 and CYP2D6 polymorphism effects on disposition and response to long-acting risperidone.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2021

Ganoci Lana, Trkulja Vladimir, Živković Maja, Božina Tamara, Šagud Marina, Lovrić Mila, Božina Nada

Abstract excerpt

The relevance of the multidrug resistance (ABCB1) and breast cancer resistance (ABCG2) protein transporter polymorphisms for treatment with long-acting intramuscular (LAI) risperidone is largely unknown. We explored the relationship between these polymorphisms and cytochrome P450 (CYP) 2D6 genotype-predicted phenotype in their effects on drug disposition and clinical outcomes in adults with schizophrenia. In a...

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Identifiers

PMID: 32682874
DOI: 10.1016/j.pnpbp.2020.110042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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