Article
Variability and additivity of read counts for aSTRs in NGS DNA profiles.
Forensic science international. Genetics - 1 Sept 2020
Cheng Kevin, Skillman Jessica, Hickey Stephanie, Just Rebecca, Moreno Lilliana, Bright Jo-Anne, Kelly Hannah, Lin Meng-Han, Curran James M, Buckleton John
Abstract excerpt
There has been an increase in the number of laboratories and researchers adopting new sequencing technologies, known as next-generation sequencing (NGS). An understanding of the behaviour of NGS DNA profiles is needed to enable for the development of probabilistic genotyping methods for the interpretation of such profiles. In this work, we investigate NGS analyte signal variation, specifically heterozygous...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.