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Implementation and validation of an improved allele specific stutter filtering method for electropherogram interpretation.

Forensic science international. Genetics - 1 Jul 2018

Kalafut Tim, Schuerman Curt, Sutton Joel, Faris Tom, Armogida Luigi, Bright Jo-Anne, Buckleton John, Taylor Duncan

Abstract excerpt

Modern probabilistic genotyping (PG) software is capable of modeling stutter as part of the profile weighting statistic. This allows for peaks in stutter positions to be considered as allelic or stutter or both. However, prior to running any sample through a PG calculator, the examiner must first interpret the sample, considering such things as artifacts and number of contributors (NOC or N). Stutter can play a...

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PMID: 29660688
DOI: 10.1016/j.fsigen.2018.03.016

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