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Article

Several Plasmodium vivax relapses after correct primaquine treatment in a patient with impaired cytochrome P450 2D6 function.

Malaria journal - 17 Jul 2020

Martin Ramírez Alexandra, Lombardia González Carlos, Soler Maniega Tamara, Gutierrez Liarte Ángela, Domingo García Diego, Lanza Suárez Marta, Bernal Fernández María Josefa, Rubio José Miguel

Abstract excerpt

BACKGROUND: Plasmodium vivax malaria is characterized by the presence of dormant liver-stage parasites, called hypnozoites, which can cause malaria relapses after an initial attack. Primaquine, which targets liver hypnozoites, must be used in combination with a schizonticidal agent to get the radical cure. However, relapses can sometimes occur in spite of correct treatment, due to different factors such as a...

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Identifiers

PMID: 32680522
DOI: 10.1186/s12936-020-03326-1
PMCID: PMC7368755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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