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Article

Human leukocyte antigen G polymorphism is associated with an increased risk of invasive cancer of the uterine cervix.

International journal of cancer - 1 Aug 2012

Ferguson Rhea, Ramanakumar Agnihotram V, Koushik Anita, Coutlée François, Franco Eduardo, Roger Michel

Abstract excerpt

Human leukocyte antigen (HLA)-G acts as negative regulator of the immune responses and its expression in tumor cells may enable them to escape immunosurveillance. The purpose of this study was to investigate the influence of HLA-G polymorphism on risk of high-grade cervical intraepithelial neoplasia (HG-CIN) and cervical cancer in a Canadian population. The authors have analyzed 1,372 women from participants...

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Identifiers

PMID: 22095460
DOI: 10.1002/ijc.27356

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