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HLA-G: A New Immune Checkpoint in Cancer?

25 Jun 2020

Abstract excerpt

Human leukocyte antigen G (HLA-G), known as a central protein in providing immune tolerance to the fetus in pregnant women, is also studied for a possible role in tumor development. Many studies have claimed HLA-G as a new immune checkpoint in cancer. Therefore, HLA-G and its receptors might be targets for immune checkpoint blockade in cancer immunotherapy. In order to substantiate that HLA-G is indeed an immune...

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PMID: 32630545
DOI: 10.3390/ijms21124528

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