Article
Association of TNF-a (rs361525 and rs1800629) with susceptibility to cervical intraepithelial lesion and cervical carcinoma in women from Republic of North Macedonia.
International journal of immunogenetics - 1 Dec 2020
Duvlis Sotirija, Dabeski Drage, Cvetkovski Aleksandar, Mladenovska Kristina, Plaseska-Karanfilska Dijana
Abstract excerpt
Cervical cancer (CCa) is one of the most common malign diseases in women associated with human papillomavirus (HPV). The virus is an initiating factor, but not sufficient for the development of cervical intraepithelial lesions (CIN) and CCa. The disease might be a result of the influence of host's genetic factors and polymorphisms in inflammatory-related genes that modify the immune response to HPV and attribute...
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