Article
A genetic polymorphism that is associated with mitochondrial energy metabolism increases risk of fibromyalgia
10 Jul 2020
Abstract excerpt
Alterations in cellular energy metabolism have been implicated in chronic pain, suggesting a role for mitochondrial DNA. Previous studies reported associations of a limited number of mitochondrial DNA polymorphisms with specific pain conditions. In this study, we examined the full mitochondrial genomes of people with a variety of chronic pain conditions. A discovery cohort consisting of 609 participants either...
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