Article
Mutation in cytochrome b gene of mitochondrial DNA in a family with fibromyalgia is associated with NLRP3-inflammasome activation.
Journal of medical genetics - 1 Feb 2016
Cordero Mario D, Alcocer-Gómez Elísabet, Marín-Aguilar Fabiola, Rybkina Tatyana, Cotán David, Pérez-Pulido Antonio, Alvarez-Suarez José Miguel, Battino Maurizio, Sánchez-Alcazar José Antonio, Carrión Angel M, Culic Ognjen, Navarro-Pando José M, Bullón Pedro
Abstract excerpt
BACKGROUND: Fibromyalgia (FM) is a worldwide diffuse musculoskeletal chronic pain condition that affects up to 5% of the general population. Many symptoms associated with mitochondrial diseases are reported in patients with FM such as exercise intolerance, fatigue, myopathy and mitochondrial dysfunction. In this study, we report a mutation in cytochrome b gene of mitochondrial DNA (mtDNA) in a family with FM with...
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