MutCombinator: identification of mutated peptides allowing combinatorial mutations using nucleotide-based graph search.

Abstract excerpt

MOTIVATION: Proteogenomics has proven its utility by integrating genomics and proteomics. Typical approaches use data from next-generation sequencing to infer proteins expressed. A sample-specific protein sequence database is often adopted to identify novel peptides from matched mass spectrometry-based proteomics; nevertheless, there is no software that can practically identify all possible forms of mutated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Databases, Protein
• Share to Mutation
• Share to Nucleotides