Article
Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease.
Nutrients - 29 Apr 2020
Perez-Diaz-Del-Campo Nuria, Abete Itziar, Cantero Irene, Marin-Alejandre Bertha Araceli, Monreal J Ignacio, Elorz Mariana, Herrero José Ignacio, Benito-Boillos Alberto, Riezu-Boj Jose I, Milagro Fermín I, Tur Josep A, Martinez J Alfredo, Zulet M Angeles
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide. Some genetic variants might be involved in the progression of this disease. The study hypothesized that individuals with the rs7359397 T allele have a higher risk of developing severe stages of NAFLD compared with non-carriers where dietary intake according to genotypes could have a key role on the pathogenesis of the disease....
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