Article
Anti-CASPR2 clinical phenotypes correlate with HLA and immunological features.
Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2020
Muñiz-Castrillo Sergio, Joubert Bastien, Elsensohn Mad-Hélénie, Pinto Anne-Laurie, Saint-Martin Margaux, Vogrig Alberto, Picard Géraldine, Rogemond Véronique, Dubois Valérie, Tamouza Ryad, Maucort-Boulch Delphine, Honnorat Jérôme
Abstract excerpt
OBJECTIVE: Antibodies against contactin-associated protein-like 2 (CASPR2-Abs) have been described in acquired neuromyotonia, limbic encephalitis (LE) and Morvan syndrome (MoS). However, it is unknown whether these constitute one sole spectrum of diseases with the same immunopathogenesis or three distinct entities with different mechanisms. METHODS: A cluster analysis of neurological symptoms was performed in a...
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