Comparative transcriptomic analysis identifies distinct molecular signatures and regulatory networks of chondroclasts and osteoclasts

Abstract excerpt

BACKGROUND: Chondroclasts and osteoclasts have been previously identified as the cells capable of resorbing mineralized cartilage and bone matrices, respectively. While both cell types appear morphologically similar, contain comparable ultrastructural features, and express tartrate-resistant acid phosphatase (TRAP), however, no information is available about the genomic similarities and differences between...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone health and osteoporosis research
• Share to Bone Metabolism and Diseases
• Share to Osteoarthritis Treatment and Mechanisms